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[FAO] TIME - YOUR MOST PRECIOUS RESOURCE




                                                                                                                                                     
AN EYE OPENER !!
TIME - YOUR MOST PRECIOUS RESOURCE

When the angel of death came to Joe Smith, to accompany him to his real home, Joe dismissively responded "I am not ready to die as I have so much left to do. Do you mind coming back later?"

The Angel replied, sorry your time is up and we must leave now.

Joe enquired, "don't you know who I am? I am Joe Smith, one of the richest men in the world.

The Angel nodded "I know all about you as I do everyone else; now hurry along, Let's go."

Joe pleaded; "if I were to give you 10% of my fortune, which is over a billion dollars, will you turn a blind eye and return a year later?"

The Angel shook his head and replied, "you don't seem to understand Joe. It is time to go"

For the next few moments, Joe tried his best to negotiate with the angel giving away more of his fortune for lesser time. He finally succumbed and offered "if I were to give you all my fortune, which is 10 billion dollars, will you give me 5 minutes so that I can call my wife and children and tell them that I love them? I have never told them this and it is very important to me that they know how I feel about them. I also need to seek forgiveness from 2 people that I have hurt the most. All I ask is 5 minutes!"

The Angel paused and looked at Joe curiously and asked, "how long did it take you to make your 10 billion dollars?"

Joe replied, "30 years my friend – it took me a whole 30 years – it's a great deal in exchange for 5 minutes, take it – you will never have to work another day in your life. "

The Angel shook his head and said "I really do not understand you human beings! If you are willing to give up 30 years of your lives' work for 5 minutes, then why did you not make the most of every minute while you had it? How did you value your time? Where were your priorities? Why did you not say or do the things that really mattered?"

The lights went off a second later, Joe was gone. His 10 billion dollars could not buy him the time to do what really mattered
.
 

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[FAO] Bypass Surgery Might Be History Soon...





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In a ground breaking discovery that may eventually render bypass surgery history, researchers at Tel Aviv University have shown that an injected protein can regrow blood vessels in the human heart.

In heart disease, blood vessels are either clogged or die off, starving the heart of oxygen and leaving it highly susceptible to a cardiac attack.

Dr. Britta Hardy of TAU's Sackler School of Medicine and her team of researchers have developed a protein-based injection that when delivered straight to muscles in the body, sparks the regrowth of tiny blood vessels.

The new vessels in the heart could give millions of people around the world a new lease on life.

"The biotechnology behind our human-based protein therapy is very complicated, but the goal is simple and the solution is straightforward. We intend to inject our drug locally to heal any oxygen-starved tissue.

So far in animal models, we've seen no side effects and no inflammation following our injection of the drug into the legs. The growth of new blood vessels happens within a few weeks, showing improved blood circulation," said Hardy.

The protein solution can also be added as a coating to a stent. Usually, the implantation of a stent is accompanied by a high risk for blood clots, which necessitates the use of blood thinners.

"We could coat a stent with our peptide, attracting endothelial stem cells to form a film on the surface of the stent. These endothelial cells on the stent would eliminate the need for taking the blood thinners that prevent blood clots from forming," said Hardy.

If investment goals are met, the researchers are hoping that toxicity studies and Phase I trials could be complete within two years.

The researchers began the study for preventing leg amputations, positing that proteins from the human body could be used to trigger the growth of new blood vessels.

Hardy started by studying a library of peptides and testing them in the laboratory and later confirmed initial results. She then took some of the isolated and synthesized peptides and tested them in diabetic mice whose legs were in the process of dying.

Although diabetes is known to decrease blood circulation, Hardy found that her therapy reversed the decrease. "Within a short time we saw the formation of capillaries and tiny blood vessels.

After three weeks, they had grown and merged together with the rest of the circulatory system," she said. In mice with limited blood circulation, she was able to completely restore blood vessels and save their legs.

It was then a short step to studying the applicability of the research to cardiac patients. "It''s pretty obvious if there is regrowth or not.

Our technology promises to regrow blood vessels like a net, and a heart that grows more blood vessels becomes stronger. It's now imaginable that, in the distant future, peptide injections may be able to replace bypass surgeries," concluded Hardy.

The study has been published in Biochemical Pharmacology 



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